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1

Conformation of the native HIV-1 envelope protein raises questions for vaccine design

Trkola, Alexandra

Journal:

Year:

2019

Language:

english

File:

PDF, 1.00 MB

english, 2019

2

OMIP-047: High-Dimensional phenotypic characterization of B cells

Liechti, Thomas, Günthard, Huldrych F., Trkola, Alexandra

Journal:

Cytometry Part A

Year:

2018

Language:

english

File:

PDF, 420 KB

english, 2018

3

Lower Broadly Neutralizing Antibody Responses in Female Versus Male HIV-1 Infected Injecting Drug Users

EULER, Zelda, VAN DEN KERKHOF, Tom L., KOUYOS, Roger D., TULLY, Damien C., ALLEN, Todd M., TRKOLA, Alexandra, SANDERS, Rogier W., SCHUITEMAKER, Hanneke, VAN GILS, Marit J.

Journal:

Year:

2019

Language:

english

File:

PDF, 729 KB

english, 2019

4

Conformation of the native HIV-1 envelope protein raises questions for vaccine design

Trkola, Alexandra

Journal:

Year:

2019

File:

PDF, 1.00 MB

2019

5

Co-receptors for HIV-1 entry

John P Moore, Alexandra Trkola, Tatjana Dragic

Journal:

Current Opinion in Immunology

Year:

1997

Language:

english

File:

PDF, 1.24 MB

english, 1997

6

HIV: Potency needs constancy

Trkola, Alexandra

Journal:

Year:

2014

Language:

english

File:

PDF, 786 KB

english, 2014

7

Broadly resistant HIV-1 against CD4-binding site neutralizing antibodies

Zhou, Panpan, Wang, Han, Fang, Mengqi, Li, Yangyang, Wang, Hua, Shi, Shasha, Li, Zihao, Wu, Jiapeng, Han, Xiaoxu, Shi, Xuanling, Shang, Hong, Zhou, Tongqing, Zhang, Linqi, Trkola, Alexandra

Journal:

Year:

2019

File:

PDF, 9.89 MB

2019

8

Interactions of Polyclonal and Monoclonal Anti-Glycoprotein 120 Antibodies with Oligomeric Glycoprotein 120-Glycoprotein 41 Complexes of a Primary HIV Type 1 Isolate: Relationship to Neutralization

FOUTS, TIMOTHY R., TRKOLA, ALEXANDRA, FUNG, MICHAEL S., MOORE, JOHN P.

Journal:

AIDS Research and Human Retroviruses

Year:

1998

Language:

english

File:

PDF, 2.14 MB

english, 1998

9

Loss of Viral Control in Early HIV‐1 Infection Is Temporally Associated with Sequential Escape from CD8 + T Cell Responses and Decrease in HIV–1–Specific CD4 + and CD8 + T Cell Frequencies

Oxenius, Annette, Price, David A., Trkola, Alexandra, Edwards, Charles, Gostick, Emma, Zhang, Hua‐Tang, Easterbrook, Philippa J., Tun, Tin, Johnson, Andrew, Waters, Anele, Holmes, Edward C., Phillips,

Journal:

The Journal of Infectious Diseases

Year:

2004

Language:

english

File:

PDF, 783 KB

english, 2004

10

Human immunodeficiency virus type-1 (HIV-1) evades antibody-dependent phagocytosis

Gach, Johannes S., Bouzin, Margaux, Wong, Marcus P., Chromikova, Veronika, Gorlani, Andrea, Yu, Kuan-Ting, Sharma, Brijesh, Gratton, Enrico, Forthal, Donald N., Trkola, Alexandra

Journal:

Year:

2017

Language:

english

File:

PDF, 2.87 MB

english, 2017

11

Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer

Khasnis, Mukta D., Halkidis, Konstantine, Bhardwaj, Anshul, Root, Michael J., Trkola, Alexandra

Journal:

Year:

2016

Language:

english

File:

PDF, 5.86 MB

english, 2016

12

Diabetes mellitus is a risk factor for prolonged SARS-CoV-2 viral shedding in lower respiratory tract samples of critically ill patients

Buetti, NiccolÃ², Trimboli, Pierpaolo, Mazzuchelli, Timothy, Lo Priore, Elia, Balmelli, Carlo, Trkola, Alexandra, Conti, Marco, Martinetti, Gladys, Elzi, Luigia, Ceschi, Alessandro, Consonni, Vera, Og

Journal:

Endocrine (Springer)

Year:

2020

File:

PDF, 721 KB

2020

13

HIV sensitivity to neutralization is determined by target and virus producer cell properties

Mann, Axel M, Rusert, Peter, Berlinger, Livia, Kuster, Herbert, Günthard, Huldrych F, Trkola, Alexandra

Journal:

Year:

2009

Language:

english

File:

PDF, 1.22 MB

english, 2009

14

The HIV-1 Entry Process: A Stoichiometric View

Brandenberg, Oliver F., Magnus, Carsten, Regoes, Roland R., Trkola, Alexandra

Journal:

Trends in Microbiology

Year:

2015

Language:

english

File:

PDF, 1.91 MB

english, 2015

15

215 In Vivo Binding and Retention of CD4-Specific DARPin 57.2 in Macaques

Pugach, Pavel, Krarup, Anders, Gettie, Agegnehu, Kuroda, Marcelo, Blanchard, James, Jr, Michael Piatak, Lifson, Jeffrey D, Trkola, Alexandra, Robbiani, Melissa

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2011

Language:

english

File:

PDF, 2.24 MB

english, 2011

16

566. Selective and Stable Transduction of Human CD4+ T Cells In Vivo Upon Systemic Administration of CD4-Targeted Lentiviral Vectors

Zhou, Qi, Uhlig, Katharina M., Muth, Anke, Kimpel, Janine, Lévy, Camille, Münch, Robert, Seifried, Janna, Trkola, Alexandra, von Laer, Dorothee, Wels, Winfried S., Hartwig, Udo, Verhoeyen, Els, Buchho

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 277 KB

english, 2015

17

HIV Type 1 Coreceptors, Neutralization Serotypes, and Vaccine Development

MOORE, JOHN, TRKOLA, ALEXANDRA

Journal:

AIDS Research and Human Retroviruses

Year:

1997

Language:

english

File:

PDF, 814 KB

english, 1997

18

A Broadly Neutralizing Human Monoclonal Antibody against gp41 of Human Immunodeficiency Virus Type 1

PURTSCHER, MARTIN, TRKOLA, ALEXANDRA, GRUBER, GERHARD, BUCHACHER, ANDREA, PREDL, RENATE, STEINDL, FRANZ, TAUER, CHRISTA, BERGER, RUDOLF, BARRETT, NOEL, JUNGBAUER, ALOIS, KATINGER, HERMANN

Journal:

AIDS Research and Human Retroviruses

Year:

1994

Language:

english

File:

PDF, 1.21 MB

english, 1994

19

Complement dependent trapping of infectious HIV in human lymphoid tissues

Bánki, Zoltán, Kacani, Laco, Rusert, Peter, Pruenster, Monika, Wilflingseder, Doris, Falkensammer, Barbara, Stellbrink, Hans-Jürgen, Lunzen, Jan van, Trkola, Alexandra, Dierich, Manfred P, Stoiber, He

Journal:

Year:

2005

Language:

english

File:

PDF, 97 KB

english, 2005

20

Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples

Lewandowska, Dagmara W., Zagordi, Osvaldo, Geissberger, Fabienne-Desirée, Kufner, Verena, Schmutz, Stefan, Böni, Jürg, Metzner, Karin J., Trkola, Alexandra, Huber, Michael

Journal:

Year:

2017

Language:

english

File:

PDF, 990 KB

english, 2017

21

Broadly neutralizing antibodies: What is needed to move from a rare event in HIV-1 infection to vaccine efficacy?

Subbaraman, Harini, Schanz, Merle, Trkola, Alexandra

Journal:

Year:

2018

Language:

english

File:

PDF, 1.04 MB

english, 2018

22

Divergent effects of cell environment on HIV entry inhibitor activity

Rusert, Peter, Mann, Axel, Huber, Michael, von Wyl, Viktor, Günthard, Huldrych F, Trkola, Alexandra

Journal:

Year:

2009

Language:

english

File:

PDF, 820 KB

english, 2009

23

Correction to: Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples

Lewandowska, Dagmara W., Zagordi, Osvaldo, Geissberger, Fabienne-Desirée, Kufner, Verena, Schmutz, Stefan, Böni, Jürg, Metzner, Karin J., Trkola, Alexandra, Huber, Michael

Journal:

Year:

2017

Language:

english

File:

PDF, 215 KB

english, 2017

24

Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations

Upadhyay, Chitra, Feyznezhad, Roya, Yang, Weiming, Zhang, Hui, Zolla-Pazner, Susan, Hioe, Catarina E., Trkola, Alexandra

Journal:

Year:

2018

Language:

english

File:

PDF, 4.72 MB

english, 2018

25

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5

Trkola, Alexandra, Dragic, Tatjana, Arthos, James, Binley, James M., Olson, William C., Allaway, Graham P., Cheng-Mayer, Cecilia, Robinson, James, Maddon, Paul J., Moore, John P.

Journal:

Year:

1996

File:

PDF, 867 KB

1996

26

Autoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10

Finton, Kathryn A. K., Larimore, Kevin, Larman, H. Benjamin, Friend, Della, Correnti, Colin, Rupert, Peter B., Elledge, Stephen J., Greenberg, Philip D., Strong, Roland K., Trkola, Alexandra

Journal:

Year:

2013

Language:

english

File:

PDF, 9.74 MB

english, 2013

27

HIV-1 Superinfection in Women Broadens and Strengthens the Neutralizing Antibody Response

Cortez, Valerie, Odem-Davis, Katherine, McClelland, R. Scott, Jaoko, Walter, Overbaugh, Julie, Trkola, Alexandra

Journal:

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

28

HIV-1 resistance to neutralizing antibodies: Determination of antibody concentrations leading to escape mutant evolution

Magnus, Carsten, Reh, Lucia, Trkola, Alexandra

Journal:

Year:

2015

Language:

english

File:

PDF, 1.93 MB

english, 2015

29

Diverse pathways of escape from all well-characterized VRC01-class broadly neutralizing HIV-1 antibodies

Otsuka, Yuka, Schmitt, Kimberly, Quinlan, Brian D., Gardner, Matthew R., Alfant, Barnett, Reich, Adrian, Farzan, Michael, Choe, Hyeryun, Trkola, Alexandra

Journal:

Year:

2018

Language:

english

File:

PDF, 5.28 MB

english, 2018

30

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

Torrents de la Peña, Alba, Rantalainen, Kimmo, Cottrell, Christopher A., Allen, Joel D., van Gils, Marit J., Torres, Jonathan L., Crispin, Max, Sanders, Rogier W., Ward, Andrew B., Trkola, Alexandra

Journal:

Year:

2019

File:

PDF, 10.13 MB

2019

31

HIV–host interactions: vital to the virus and key to its inhibition

Alexandra Trkola

Journal:

Current Opinion in Microbiology

Year:

2004

Language:

english

File:

PDF, 133 KB

english, 2004

32

Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies

Trkola, Alexandra, Kuster, Herbert, Rusert, Peter, Joos, Beda, Fischer, Marek, Leemann, Christine, Manrique, Amapola, Huber, Michael, Rehr, Manuela, Oxenius, Annette

Journal:

Nature Medicine

Year:

2005

Language:

english

File:

PDF, 788 KB

english, 2005

33

Therapeutic Antibodies in HIV Treatment - Classical Approaches to Novel Advances

A. Abela, Irene, Reynell, Lucy, Trkola, Alexandra

Journal:

Current Pharmaceutical Design

Year:

2010

Language:

english

File:

PDF, 373 KB

english, 2010

34

Use of alternate coreceptors on primary cells by two HIV-1 isolates

Tonie Cilliers, Samantha Willey, W. Mathew Sullivan, Trudy Patience, Pavel Pugach, Mia Coetzer, Maria Papathanasopoulos, John P. Moore, Alexandra Trkola, Paul Clapham, Lynn Morris

Journal:

Year:

2005

Language:

english

File:

PDF, 560 KB

english, 2005

35

Different Infectivity of HIV-1 Strains Is Linked to Number of Envelope Trimers Required for Entry

Brandenberg, Oliver F., Magnus, Carsten, Rusert, Peter, Regoes, Roland R., Trkola, Alexandra, Emerman, Michael

Journal:

Year:

2015

Language:

english

File:

PDF, 1.03 MB

english, 2015

36

Capacity of Broadly Neutralizing Antibodies to Inhibit HIV-1 Cell-Cell Transmission Is Strain- and Epitope-Dependent

Reh, Lucia, Magnus, Carsten, Schanz, Merle, Weber, Jacqueline, Uhr, Therese, Rusert, Peter, Trkola, Alexandra, Burton, Dennis R.

Journal:

Year:

2015

Language:

english

File:

PDF, 5.84 MB

english, 2015

37

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

Torrents de la Peña, Alba, Rantalainen, Kimmo, Cottrell, Christopher A., Allen, Joel D., van Gils, Marit J., Torres, Jonathan L., Crispin, Max, Sanders, Rogier W., Ward, Andrew B., Trkola, Alexandra

Journal:

Year:

2019

Language:

english

File:

PDF, 10.13 MB

english, 2019

38

Seroprevalence and immunity of SARS-CoV-2 infection in children and adolescents in schools in Switzerland: design for a longitudinal, school-based prospective cohort study

Ulyte, Agne, Radtke, Thomas, Abela, IrÃ¨ne A., Haile, Sarah R., Braun, Julia, Jung, Ruedi, Berger, Christoph, Trkola, Alexandra, Fehr, Jan, Puhan, Milo A., Kriemler, Susi

Journal:

International Journal of Public Health

Year:

2020

File:

PDF, 562 KB

2020

39

A Luciferase-Reporter Gene-Expressing T-Cell Line Facilitates Neutralization and Drug-Sensitivity Assays That Use Either R5 or X4 Strains of Human Immunodeficiency Virus Type 1

Catherine Spenlehauer, Cynthia A. Gordon, Alexandra Trkola, John P. Moore

Journal:

Year:

2001

Language:

english

File:

PDF, 168 KB

english, 2001

40

Development of a high-throughput bead based assay system to measure HIV-1 specific immune signatures in clinical samples

Liechti, Thomas, Kadelka, Claus, Ebner, Hanna, Friedrich, Nikolas, Kouyos, Roger D., Günthard, Huldrych F., Trkola, Alexandra

Journal:

Journal of Immunological Methods

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

41

In Vivo Binding and Retention of CD4-Specific DARPin 57.2 in Macaques

Pugach, Pavel, Krarup, Anders, Gettie, Agegnehu, Kuroda, Marcelo, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Trkola, Alexandra, Robbiani, Melissa, Unutmaz, Derya

Journal:

Year:

2010

Language:

english

File:

PDF, 325 KB

english, 2010

42

HIV-1 replication activates CD4+ T cells with specificities for persistent herpes viruses

Anna Haas, Manuela Rehr, Frederik Graw, Peter Rusert, Walter Bossart, Herbert Kuster, Alexandra Trkola, Huldrych F. Günthard, Annette Oxenius

Journal:

EMBO Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 1.14 MB

english, 2010

43

Peptidomimetic inhibitors targeting the CCR5-binding site on the human immunodeficiency virus type-1 gp120 glycoprotein complexed to CD4

Seitz, Markus, Rusert, Peter, Moehle, Kerstin, Trkola, Alexandra, Robinson, John A.

Journal:

Chemical Communications

Year:

2010

Language:

english

File:

PDF, 1.29 MB

english, 2010

44

Off-target-free gene delivery by affinity-purified receptor-targeted viral vectors

Münch, Robert C., Muth, Anke, Muik, Alexander, Friedel, Thorsten, Schmatz, Julia, Dreier, Birgit, Trkola, Alexandra, Plückthun, Andreas, Büning, Hildegard, Buchholz, Christian J.

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

45

Antibody to gp41 MPER Alters Functional Properties of HIV-1 Env without Complete Neutralization

Kim, Arthur S., Leaman, Daniel P., Zwick, Michael B., Trkola, Alexandra

Journal:

Year:

2014

Language:

english

File:

PDF, 2.18 MB

english, 2014

46

HIV RNA in plasma rebounds within days during structured treatment interruptions

Fischer, Marek, Hafner, Roland, Schneider, Christine, Trkola, Alexandra, Joos, Beda, Joller, Helen, Hirschel, Bernard, Weber, Rainer, Günthard, Huldrych F

Journal:

Year:

2003

Language:

english

File:

PDF, 93 KB

english, 2003

47

High-Throughput Sequencing of Human Immunoglobulin Variable Regions with Subtype Identification

Schanz, Merle, Liechti, Thomas, Zagordi, Osvaldo, Miho, Enkelejda, Reddy, Sai T., Günthard, Huldrych F., Trkola, Alexandra, Huber, Michael, Lu, Shan

Journal:

Year:

2014

Language:

english

File:

PDF, 528 KB

english, 2014

48

Autocrine Production of β-Chemokines Protects CMV-Specific CD4+ T Cells from HIV Infection

Casazza, Joseph P., Brenchley, Jason M., Hill, Brenna J., Ayana, Ribka, Ambrozak, David, Roederer, Mario, Douek, Daniel C., Betts, Michael R., Koup, Richard A., Trkola, Alexandra

Journal:

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

49

Mathematical models: A key to understanding HIV envelope interactions?

Magnus, Carsten, Brandenberg, Oliver F., Rusert, Peter, Trkola, Alexandra, Regoes, Roland R.

Journal:

Journal of Immunological Methods

Year:

2013

Language:

english

File:

PDF, 2.79 MB

english, 2013

50

Role of Abl Kinase and the Wave2 Signaling Complex in HIV-1 Entry at a Post-Hemifusion Step

Harmon, Brooke, Campbell, Nancy, Ratner, Lee, Trkola, Alexandra

Journal:

Year:

2010

Language:

english

File:

PDF, 807 KB

english, 2010

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